Original article · Clinical Science
Open AccessFemtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus
David J. Gunn · Rebecca A. Cox · Brendan Cronin
Queensland Eye Institute, Brisbane, Queensland, Australia
- Journal
- Clinical & Experimental Ophthalmology
- Citation
- 2026; 0:1–14
- Accepted
- 1 March 2026
Methods. Retrospective case series of 85 keratoconic eyes from 75 patients. CDVA, UDVA, refraction, corneal topography and higher-order aberrations measured pre-op and at ≥ 3 months post-op. All CAIRS created with femtosecond laser; segment width, thickness, arc length, axis and channel depth determined by the Brisbane nomogram against individual topography.
CXL composition. 18 eyes had prior cross-linking, 30 underwent simultaneous CXL, 37 had no CXL.
Headline result. UDVA improved by 0.4 logMAR (p < 0.001); CDVA by 0.2 logMAR (p < 0.001). 31 eyes (43.7%) gained ≥ 5 lines. Significant reduction in spherical equivalent, refractive astigmatism, flat K, steep K, mean K and KMax. KMax reduction greater with simultaneous CXL (−4.28 D vs −0.70 D; p = 0.018). No significant complications.